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Contraindicated (one)pentobarbital will minimize the level or effect of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with potent CYP3A4 inducers can lead to diminished serum concentrations and lack of antimalarial efficacypentobarbital will lessen the extent or effect of zolpidem by impact